Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

Benzer Materyaller

• Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.
  Yazar:: Kuyper, L, ve diğerleri
  Baskı/Yayın Bilgisi: (1985)
• The binding of trimethoprim to bacterial dihydrofolate reductase.
  Yazar:: Baker, D, ve diğerleri
  Baskı/Yayın Bilgisi: (1981)
• Crystallographic investigation of the cooperative interaction between trimethoprim, reduced cofactor and dihydrofolate reductase.
  Yazar:: Champness, J, ve diğerleri
  Baskı/Yayın Bilgisi: (1986)
• Refolding of recombinant Pneumocystis carinii dihydrofolate reductase and characterization of the enzyme.
  Yazar:: Delves, C, ve diğerleri
  Baskı/Yayın Bilgisi: (1993)
• The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme.
  Yazar:: Stammers, D, ve diğerleri
  Baskı/Yayın Bilgisi: (1987)