Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.

Glucocorticoids increase adipocyte proliferation and differentiation, a process underpinned by the local reactivation of inactive cortisone to active cortisol within adipocytes catalyzed by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). The adrenal sex steroid precursor dehydroepiandrosterone (...

Повний опис

Бібліографічні деталі
Автори: McNelis, J, Manolopoulos, K, Gathercole, L, Bujalska, I, Stewart, P, Tomlinson, J, Arlt, W
Формат: Journal article
Мова:English
Опубліковано: 2013