Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.

Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.

Obesity is a major health problem, and many family-based studies have suggested that it has a strong genetic basis. We performed a genome-wide quantitative trait linkage scan for loci influencing BMI in 573 pedigrees from the U.K. We identified genome-wide significant linkage (logarithm of odds = 3....

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Detalles Bibliográficos
Main Authors: Groves, C, Zeggini, E, Walker, M, Hitman, G, Levy, J, O'Rahilly, S, Hattersley, A, McCarthy, M, Wiltshire, S
Formato: Journal article
Idioma:English
Publicado: 2006

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