Lack of association between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 subtype C Gag-protease from chronically infected individuals.

It is unknown whether favorable HLA class II alleles may attenuate HIV-1 through selection pressure in a manner similar to that of protective HLA class I alleles. We investigated the relationship between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 s...

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Bibliographic Details
Main Authors: Wright, J, Brumme, Z, Julg, B, van der Stok, M, Mncube, Z, Gao, X, Carlson, J, Goulder, P, Walker, B, Brockman, M, Ndung'u, T
Format: Journal article
Language:English
Published: 2012