EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.

Purpose Radiolabeled antibodies and peptides hold promise for molecular radiotherapy but are often limited by a low payload resulting in inadequate delivery of radioactivity to tumour tissue and, therefore, modest therapeutic effect. We developed a facile synthetic method of radiolabeling indium-111...

書誌詳細
主要な著者:	Song, L, Falzone, N, Vallis, K
フォーマット:	Journal article
言語:	English
出版事項:	Taylor and Francis 2016

類似資料

EGF Functionalized Polymer-Coated Gold Nanoparticles Promote EGF Photostability and EGFR Internalization for Photothermal Therapy.
著者:: Catarina Oliveira Silva, 等
出版事項: (2016-01-01)

Accumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Co-administration of Targeting Ligand
著者:: Song, L, 等
出版事項: (2017)

SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo
著者:: Song, L, 等
出版事項: (2016)

Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.
著者:: Chen, P, 等
出版事項: (2002)

111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.
著者:: Reilly, R, 等
出版事項: (2000)

In-111-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR
著者:: Reilly, R, 等
出版事項: (2000)

Gold-Coated Superparamagnetic Iron Oxide Nanoparticles Functionalized to EGF and Ce6 Complexes for Breast Cancer Diagnoses and Therapy
著者:: Marcela Cândido, 等
出版事項: (2022-12-01)

Photothermal and radiotherapy with alginate-coated gold nanoparticles for breast cancer treatment
著者:: Mohammadreza Ghaffarlou, 等
出版事項: (2024-06-01)

Gold coated lanthanide phosphate nanoparticles for targeted alpha generator radiotherapy.
著者:: Mark F McLaughlin, 等
出版事項: (2013-01-01)

Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
著者:: Cornelissen, B, 等
出版事項: (2013)

RIZ2 at the crossroad of the EGF/EGFR signaling in colorectal cancer
著者:: Marzia Di Donato, 等
出版事項: (2023-10-01)

Amplified delivery of indium-111 to EGFR-positive human breast cancer cells.
著者:: Wang, J, 等
出版事項: (2001)

Trimethyl-Chitosan Coated Gold Nanoparticles Enhance Delivery, Cellular Uptake and Gene Silencing Effect of EGFR-siRNA in Breast Cancer Cells
著者:: Leila Baghani, 等
出版事項: (2022-04-01)

Effect of the EGFR density of breast cancer cells on nuclear importation, in vitro cytotoxicity, and tumor and normal-tissue uptake of [111In]DTPA-hEGF.
著者:: Hu, M, 等
出版事項: (2007)

Radiotherapy-induced enrichment of EGF-modified doxorubicin nanoparticles enhances the therapeutic outcome of lung cancer
著者:: Jing Wang, 等
出版事項: (2022-12-01)

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.
著者:: Cornelissen, B, 等
出版事項: (2013)

Expression of EGF, EGFR, and proliferation in placentas from pregnancies complicated with preeclampsia
著者:: Indira Kosovic, 等
出版事項: (2017-01-01)

Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation
著者:: Jianchao Zheng, 等
出版事項: (2017-09-01)

HCC-derived EGFR mutants are functioning, EGF-dependent, and erlotinib-resistant
著者:: Natthaporn Sueangoen, 等
出版事項: (2020-03-01)

Enhancing Radiotherapy by Lipid Nanocapsule-Mediated Delivery of Amphiphilic Gold Nanoparticles to Intracellular Membranes
著者:: Yang, Yu-Sang Sabrina, 等
出版事項: (2015)

Laser-Induced Intracellular Delivery: Exploiting Gold-Coated Spiky Polymeric Nanoparticles and Gold Nanorods under Near-Infrared Pulses for Single-Cell Nano-Photon-Poration
著者:: Ashish Kumar, 等
出版事項: (2024-01-01)

A novel EGFR-targeted gene delivery system based on complexes self-assembled by EGF, DNA, and activated PAMAM dendrimers
著者:: Yin Z, 等
出版事項: (2012-08-01)

β-Catenin nuclear localization positively feeds back on EGF/EGFR-attenuated AJAP1 expression in breast cancer
著者:: Cong Xu, 等
出版事項: (2019-06-01)

USP25 Regulates EGFR Fate by Modulating EGF-Induced Ubiquitylation Dynamics
著者:: Carlos A. Niño, 等
出版事項: (2020-11-01)

Deficiency of GABARAP but Not Its Paralogs Causes Enhanced EGF-Induced EGFR Degradation
著者:: Jochen Dobner, 等
出版事項: (2020-05-01)

PKG II inhibits EGF/EGFR-induced migration of gastric cancer cells.
著者:: Lu Jiang, 等
出版事項: (2013-01-01)

SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR.
著者:: J Terrig Thomas, 等
出版事項: (2016-01-01)

Differential Expression Patterns of EGF, EGFR, and ERBB4 in Nasal Polyp Epithelium.
著者:: Chen Duan, 等
出版事項: (2016-01-01)

Platelet Membranes Coated Gold Nanocages for Tumor Targeted Drug Delivery and Amplificated Low-Dose Radiotherapy
著者:: Mingzhu Chen, 等
出版事項: (2021-11-01)

Evaluation of CTAB coated gold nanoparticles as a potential carrier for gene delivery
著者:: Sepideh Pouya, 等
出版事項: (2022-09-01)

Chemically amplified photoresist for high resolution autoradiography in targeted radiotherapy.
著者:: Falzone, N, 等
出版事項: (2011)

Inhibition of EGFR attenuates EGF-induced activation of retinal pigment epithelium cell via EGFR/AKT signaling pathway
著者:: Yu-Sheng Zhu, 等
出版事項: (2024-06-01)

Irradiation stability and cytotoxicity of gold nanoparticles for radiotherapy
著者:: Xiao-Dong Zhang, 等
出版事項: (2009-09-01)

Revolutionizing radiotherapy: gold nanoparticles with polyphenol coating as novel enhancers in breast cancer cells—an in vitro study
著者:: Simona Tarantino, 等
出版事項: (2025-01-01)

Delay of EGF-Stimulated EGFR Degradation in Myotonic Dystrophy Type 1 (DM1)
著者:: Eva Alegre-Cortés, 等
出版事項: (2022-09-01)

Cellular Uptake of Silica Particles Influences EGFR Signaling Pathway and is Affected in Response to EGF
著者:: Sousa de Almeida M, 等
出版事項: (2023-02-01)

Dendrimer-Coated Gold Nanoparticles for Efficient Folate-Targeted mRNA Delivery In Vitro
著者:: Londiwe Simphiwe Mbatha, 等
出版事項: (2021-06-01)

Internalization of Phospholipid-Coated Gold Nanoparticles
著者:: Lindsay J. Shearer, 等
出版事項: (2019-10-01)

One-Step Synthesis of Polypyrrole-Coated Gold Nanoparticles for Use as a Photothermally Active Nano-System
著者:: Fadel M, 等
出版事項: (2020-04-01)

Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides
著者:: Bavelaar, BM, 等
出版事項: (2021)