Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

BACKGROUND: Inhibition of parasite growth is a major objective of blood-stage malaria vaccines. The in vitro assay of parasite growth inhibitory activity (GIA) is widely used as a surrogate marker for malaria vaccine efficacy in the down-selection of candidate blood-stage vaccines. Here we report th...

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Bibliographic Details
Main Authors: Duncan, C, Sheehy, S, Ewer, K, Douglas, A, Collins, K, Halstead, F, Elias, S, Lillie, P, Rausch, K, Aebig, J, Miura, K, Edwards, N, Poulton, I, Hunt-Cooke, A, Porter, D, Thompson, F, Rowland, R, Draper, S, Gilbert, S, Fay, M, Long, C, Zhu, D, Wu, Y, Martin, L, Anderson, C, Lawrie, A, Hill, A, Ellis, R
Format: Journal article
Language:English
Published: Public Library of Science 2011