E-cadherin loss of function in the murine intestine
<p>E-cadherin (<em>Cdh1</em>), is a major component of epithelial adherens junctions, binds the Wnt pathway effector β-catenin and is lost at the invasive edge of colon cancers. Crypt stem cells give rise to 4 cell lineages that, with the exception of Paneth cells, travel along the...
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Format: | Thesis |
Language: | English |
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2012
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