E-cadherin loss of function in the murine intestine

<p>E-cadherin (<em>Cdh1</em>), is a major component of epithelial adherens junctions, binds the Wnt pathway effector β-catenin and is lost at the invasive edge of colon cancers. Crypt stem cells give rise to 4 cell lineages that, with the exception of Paneth cells, travel along the...

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Bibliographic Details
Main Author: Matheson, JAH
Other Authors: Hassan, AB
Format: Thesis
Language:English
Published: 2012
Subjects:

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