Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.

BACKGROUND: Intra-rectal artesunate has been developed as a potentially life-saving treatment of severe malaria in rural village settings where administration of parenteral antimalarial drugs is not possible. We studied the population pharmacokinetics of intra-rectal artesunate and the relationship...

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Bibliographic Details
Main Authors:	Simpson, J, Agbenyega, T, Barnes, K, Di Perri, G, Folb, P, Gomes, M, Krishna, S, Krudsood, S, Looareesuwan, S, Mansor, S, McIlleron, H, Miller, R, Molyneux, M, Mwenechanya, J, Navaratnam, V, Nosten, F, Olliaro, P, Pang, L, Ribeiro, I, Tembo, M, van Vugt, M, Ward, S, Weerasuriya, K, Win, K, White, N
Format:	Journal article
Language:	English
Published:	Public Library of Science 2006

Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.

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