Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.

OBJECTIVES: Genome-wide association studies have dramatically increased the number of common genetic variants that are robustly associated with type 2 diabetes. A possible clinical use of this information is to identify individuals at high risk of developing the disease, so that preventative measur...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Lango, H, Palmer, C, Morris, A, Zeggini, E, Hattersley, A, McCarthy, M, Frayling, T, Weedon, M
פורמט:	Journal article
שפה:	English
יצא לאור:	2008

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Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI.
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