Structural, biochemical and inhibition studies on hypoxia-inducible factor (HIF) prolyl hydroxylases
<p>In humans and other animals, the chronic hypoxic response is mediated by the hypoxia-inducible transcription factors (HIFs), which regulate the expression of genes that counteract the effects of limiting oxygen. HIF prolyl hydroxylases (PHDs) regulate cellular levels and transcriptional act...
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| Format: | Thesis |
| Language: | English |
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2018
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