A role for 5-HT in the action of antidepressant drugs.
Administration of antidepressant drugs to rodents appears to decrease 5-HT2 receptor function while transmission through postsynaptic 5-HT1 receptor synapses may be enhanced. Antidepressant drugs also alter 5-HT mechanisms in humans; some of these changes are congruent with effects noted in animal s...
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1990
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