Vaccination for hepatitis C - characterising the host immune response and its implications for a successful therapeutic vaccine

Vaccination for hepatitis C - characterising the host immune response and its implications for a successful therapeutic vaccine

<p>This thesis explores the first-ever administration of a prime/boost combination of adenovirus and MVA vector based vaccines that target hepatitis C virus (HCV) infection to humans. Therapeutic application of these vaccines in patients with chronic HCV infection is first detailed, together w...

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Bibliografiske detaljer
Main Authors:	Halliday, J, John Halliday
Andre forfattere:	Barnes, E
Format:	Thesis
Sprog:	English
Udgivet:	2013
Fag:	Immunology

Lignende værker

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
af: Antrobus, R
Udgivet: (2014)

Characterising novel vaccine adjuvants in eliciting antigen-specific CD8+ T cell immunity
af: He, A
Udgivet: (2023)

The development of novel therapeutic vaccines for chronic hepatitis B infection
af: Cargill, TN
Udgivet: (2021)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
af: Hennig, B, et al.
Udgivet: (2008)

Predictive signatures of immune response to vaccination and implications of the immune setpoint remodeling
af: Irene Ramos
Udgivet: (2025-02-01)

Novel adenoviral vectored vaccines and the implications of viral diversity in therapeutic strategies against Hepatitis C Virus infection
af: Kelly, C
Udgivet: (2013)

The development of a hepatitis C virus prophylactic vaccine strategy
af: Donnison, T
Udgivet: (2019)

Immune responses to Neisseria gonorrhoeae and implications for vaccine development
af: Thomas Belcher, et al.
Udgivet: (2023-08-01)

Hepatitis B vaccination
af: Pollard, A
Udgivet: (2007)

The innate immune response following multivalent dengue vaccination and implications for protection against dengue challenge
af: Ruixue Hou, et al.
Udgivet: (2022-06-01)

Single-cell characterisation of T lymphocyte immune responses in spondyloarthropathy
af: Penkava, F
Udgivet: (2019)

Immunotherapy is different: Implications for vaccine clinical trial design
af: Richard Simon
Udgivet: (2017-09-01)

Towards improved blood-stage malaria vaccines: characterising the underlying immunogenicity of vaccine adjuvants and vectors
af: de Cassan, S
Udgivet: (2011)

A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine
af: Adam-Nicolas Pelletier, et al.
Udgivet: (2024-07-01)

The mechanistic modelling and simulation of vaccine-adjuvant induced immune responses
af: Buckley, PR
Udgivet: (2021)

Understanding dengue pathogenesis: implications for vaccine design
af: Stephenson John R.
Udgivet: (2005-01-01)

Vaccination for hepatitis C virus: closing in on an evasive target.
af: Halliday, J, et al.
Udgivet: (2011)

Nanostructured SBA-15 silica as an adjuvant in immunizations with hepatitis B vaccine
af: Karina Scaramuzzi, et al.
Udgivet: (2011-12-01)

Nanostructured SBA-15 silica as an adjuvant in immunizations with hepatitis B vaccine
af: Karina Scaramuzzi, et al.
Udgivet: (2011-12-01)

Genetic and molecular technologies to optimise novel vaccines for Hepatitis C virus infection
af: Swadling, L
Udgivet: (2015)

Timing and implications for immune response to vaccine in SARS-CoV-2 breakthrough infections
af: Stefania Arsuffi, et al.
Udgivet: (2023-05-01)

Characterising the T cell responses to SARS-CoV-2 including variants of concern induced by natural infection and vaccines
af: Adele, S
Udgivet: (2024)

Characterization of recombinant gorilla adenovirus HPV therapeutic vaccine PRGN-2009
af: Samuel T. Pellom, et al.
Udgivet: (2021-04-01)

Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine
af: Beatriz F. Carniel, et al.
Udgivet: (2021-02-01)

Characterising the immune response to combined skin and solid organ transplants
af: Stark, H
Udgivet: (2022)

Evaluation of immune correlates to TB vaccines
af: Marsay, L
Udgivet: (2011)

Epithelial dendritic cells vs. Langerhans cells: Implications for mucosal vaccines
af: Erica Elizabeth Vine, et al.
Udgivet: (2024-04-01)

The immune duality of osteopontin and its therapeutic implications for kidney transplantation
af: Junto Leung, et al.
Udgivet: (2025-02-01)

Impact of peripheral mitochondrial DNA level on immune response after COVID-19 vaccination
af: Hiroaki Ikezaki, et al.
Udgivet: (2023-07-01)

Intradermal vaccination of adults with three low doses (2 µg) of recombinant hepatitis B vaccine. II. Persistence of immunity and induction of immunologic memory
af: Maria do Carmo M Elisbão, et al.
Udgivet: (2003-12-01)

The characterisation of intestinal dendritic cells and the control of immune responses towards the microbiota
af: Johnson, A
Udgivet: (2011)

Immune profiling of responses to influenza vaccination in patients with myeloproliferative neoplasms
af: Petra Bachanová, et al.
Udgivet: (2024-06-01)

Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
af: Jack Mellors, et al.
Udgivet: (2020-07-01)

Implications of HCV genotype 3 specific immunity on cross-reactive vaccine design
af: von Delft, A, et al.
Udgivet: (2014)

Immune memory shapes human polyclonal antibody responses to H2N2 vaccination
af: Yuhe R. Yang, et al.
Udgivet: (2024-05-01)

HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
af: Xiaoqing Shi, et al.
Udgivet: (2023-03-01)

Evaluation of the immunogenicity of a promising vaccine regimen to identify immune correlates of protection
af: Pinpathomrat, N
Udgivet: (2018)

Immune responses against group B Streptococcus monovalent and pentavalent capsular polysaccharide tetanus toxoid conjugate vaccines in Balb/c mice
af: Nisha Dhar, et al.
Udgivet: (2023-08-01)

Persistence of anti-HBs and immunologic memory in children immunized with hepatitis B vaccine
af: Sharif Md Habibur Rahman, et al.
Udgivet: (2023-06-01)

Innate immune responses to tuberculosis vaccines
af: Matsumiya, M
Udgivet: (2014)