Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry

Genome-wide polygenic risk scores (GW-PRSs) have been reported to have better predictive ability than PRSs based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several GW-PRS approaches to a recently developed PRS of 269 established prostate canc...

Full description

Bibliographic Details
Main Authors: Darst, BF, Hunter, DJ, Shen, J, Madduri, RK, Neal, DE, Travis, RC
Other Authors: Australian Prostate Cancer BioResource
Format: Journal article
Language:English
Published: Cell Press 2023