Precision modulation of neurodegenerative disease-related gene expression in human iPSC-derived neurons

The ability to reprogram adult somatic cells into induced pluripotent stem cells (iPSCs) and the subsequent development of protocols for their differentiation into disease-relevant cell types have enabled in-depth molecular analyses of multiple disease states as hitherto impossible. Neurons differen...

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Hlavní autoři: Heman-Ackah, S, Bassett, A, Wood, M
Médium: Journal article
Vydáno: Springer Nature 2016