Kinetic resolution of tert-butyl (RS)-3-alkylcyclopentene-1-carboxylates for the synthesis of homochiral 3-alkyl-cispentacin and 3-alkyl-transpentacin derivatives.

High levels of stereocontrol are observed in the conjugate addition of lithium dibenzylamide to tert-butyl (RS)-3-alkylcyclopentene-1-carboxylates (alkyl = Et, Bn), with addition occurring exclusively anti- to the 3-alkyl substituent. Treatment of a range of tert-butyl (RS)-3-alkylcyclopentene-1-car...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Bunnage, M, Davies, S, Parkin, R, Roberts, P, Smith, A, Withey, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2004