Isolation of the human chromosomal band Xq28 within somatic cell hybrids by fragile X site breakage.
The chromosomal fragile-site mapping to Xq27.3 is associated with a frequent form of mental retardation and is prone to breakage after induced deoxyribonucleotide pool perturbation. The human hypoxanthine phosphoribosyltransferase (HPRT) and glucose-6-phosphate dehydrogenase (G6PD) genes flank the f...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1990
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