Influenza A virus challenge models in Cynomolgus macaques using the authentic inhaled aerosol and intra-nasal routes of infection

Non-human primates are the animals closest to humans for use in influenza A virus challenge studies, in terms of their phylogenetic relatedness, physiology and immune systems. Previous studies have shown that cynomolgus macaques (Macaca fascicularis) are permissive for infection with H1N1pdm influen...

Full description

Bibliographic Details
Main Authors: Marriott, A, Dennis, M, Kane, J, Gooch, K, Hatch, G, Sharpe, S, Prevosto, C, Leeming, G, Zekeng, E, Staples, K, Hall, G, Ryan, K, Bate, S, Moyo, N, Whittaker, C, Hallis, B, Silman, N, Lalvani, A, Wilkinson, T, Hiscox, J, Stewart, J, Carroll, M
Other Authors: Pöhlmann, S
Format: Journal article
Published: Public Library of Science 2016