A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs.

The quiescent cell population of tumours poses a barrier to the success of many cancer therapies. Most chemotherapeutic drugs target proliferating cells, but the growth fraction of many tumours is low. Based on the multicellular tumour spheroid model, a system was developed using human colon adenoca...

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Bibliographic Details
Main Authors: Mellor, H, Ferguson, D, Callaghan, R
Format: Journal article
Language:English
Published: 2005