A model of quiescent tumour microregions for evaluating multicellular resistance to chemotherapeutic drugs.
The quiescent cell population of tumours poses a barrier to the success of many cancer therapies. Most chemotherapeutic drugs target proliferating cells, but the growth fraction of many tumours is low. Based on the multicellular tumour spheroid model, a system was developed using human colon adenoca...
Main Authors: | Mellor, H, Ferguson, D, Callaghan, R |
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Format: | Journal article |
Language: | English |
Published: |
2005
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