A multiphase model for chemically- and mechanically- induced cell differentiation in a hollow fibre membrane bioreactor: minimising growth factor consumption

We present a simplified two-dimensional model of fluid flow, solute transport, and cell distribution in a hollow fibre membrane bioreactor. We consider two cell populations, one undifferentiated and one differentiated, with differentiation stimulated either by growth factor alone, or by both growth...

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Bibliographic Details
Main Authors: Pearson, N, Oliver, J, Shipley, R, Waters, S
Format: Journal article
Language:English
Published: Springer Verlag 2015