A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T‐cell activation

CD5 and CD6 are related surface receptors that limit and promote T‐cell responses. Co‐stimulatory effects of CD6 depend on binding a cell surface ligand, CD166, and recruitment of the intracellular adaptor proteins GADS and SLP‐76 by C‐terminal phosphotyrosines. We have continued to identify interac...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Breuning, J, Brown, M
Fformat: Journal article
Cyhoeddwyd: Wiley 2018