A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T‐cell activation
CD5 and CD6 are related surface receptors that limit and promote T‐cell responses. Co‐stimulatory effects of CD6 depend on binding a cell surface ligand, CD166, and recruitment of the intracellular adaptor proteins GADS and SLP‐76 by C‐terminal phosphotyrosines. We have continued to identify interac...
| Главные авторы: | , |
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| Формат: | Journal article |
| Опубликовано: |
Wiley
2018
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