A sequence conserved between CD5 and CD6 binds an FERM domain and exerts a restraint on T‐cell activation
CD5 and CD6 are related surface receptors that limit and promote T‐cell responses. Co‐stimulatory effects of CD6 depend on binding a cell surface ligand, CD166, and recruitment of the intracellular adaptor proteins GADS and SLP‐76 by C‐terminal phosphotyrosines. We have continued to identify interac...
| Những tác giả chính: | , |
|---|---|
| Định dạng: | Journal article |
| Được phát hành: |
Wiley
2018
|