The inositol-3-phosphate synthase biosynthetic enzyme has distinct catalytic and metabolic roles

Inositol levels, maintained by the biosynthetic enzyme inositol-3-phosphate synthase (Ino1), are altered in a range of disorders, including bipolar disorder and Alzheimer's disease. To date, most inositol studies have focused on the molecular and cellular effects of inositol depletion without c...

Full description

Bibliographic Details
Main Authors: Frej, A, Clark, J, Le Roy, C, Lilla, S, Thomason, P, Otto, G, Churchill, G, Insall, R, Claus, S, Hawkins, P, Stephens, L, Williams, R
Format: Journal article
Language:English
Published: American Society for Microbiology 2016