Quinine loading dose in cerebral malaria.

In cerebral malaria, the use of currently recommended doses of intravenous quinine may result in subtherapeutic plasma concentrations during the critical first 24 hours of treatment. A loading dose of quinine (20 mg/kg quinine dihydrochloride, equivalent to 16.7 mg/kg base, infused over 4 hours) pro...

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Bibliographic Details
Main Authors: White, N, Looareesuwan, S, Warrell, D, Warrell, M, Chanthavanich, P, Bunnag, D, Harinasuta, T
Format: Journal article
Language:English
Published: 1983