Phase I trial of intravesical Suramin in recurrent superficial transitional cell bladder carcinoma.

Suramin is an antitrypanosomal agent with antineoplastic activity, but with serious systemic side effects. We administered Suramin intravesically to determine a concentration with low toxicity but with evidence of a pharmacodynamic effect, to recommend a dose level for phase II trials. This was an o...

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Bibliographic Details
Main Authors: Ord, J, Streeter, E, Jones, A, Le Monnier, K, Cranston, D, Crew, J, Joel, S, Rogers, M, Banks, R, Roberts, I, Harris, A
Format: Journal article
Language:English
Published: 2005