Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.

Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein. Approximately 5-10% of PD patients have a familial form of Parkinsonis...

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Bibliografski detalji
Glavni autori: Taylor, T, Potgieter, D, Anwar, S, Senior, S, Janezic, S, Threlfell, S, Ryan, B, Parkkinen, L, Deltheil, T, Cioroch, M, Livieratos, A, Oliver, P, Jennings, K, Davies, K, Ansorge, O, Bannerman, D, Cragg, S, Wade-Martins, R
Format: Journal article
Jezik:English
Izdano: Elsevier 2014

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