Meta-analysis of gene-level tests for rare variant association.

Meta-analysis of gene-level tests for rare variant association.

Diğer sürümleri göster (1)

The majority of reported complex disease associations for common genetic variants have been identified through meta-analysis, a powerful approach that enables the use of large sample sizes while protecting against common artifacts due to population structure and repeated small-sample analyses sharin...

Detaylı Bibliyografya
Asıl Yazarlar:	Liu, D, Peloso, G, Zhan, X, Holmen, O, Zawistowski, M, Feng, S, Nikpay, M, Auer, P, Goel, A, Zhang, H, Peters, U, Farrall, M, Orho-Melander, M, Kooperberg, C, McPherson, R, Watkins, H, Willer, C, Hveem, K, Melander, O, Kathiresan, S, Abecasis, G
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2014

Benzer Materyaller

Meta-analysis of gene-level tests for rare variant association
Yazar:: Liu, D, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia.
Yazar:: Stitziel, N, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia
Yazar:: Stitziel, N, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

New insights into impaired muscle glycogen synthesis.
Yazar:: Leif Groop, ve diğerleri
Baskı/Yayın Bilgisi: (2008-01-01)

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.
Yazar:: Orho-Melander, M, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Functional characterisation of the glucokinase regulatory protein gene variant P446L shows diminished regulation by fructose-6 phosphate resulting in increased glucokinase activity
Yazar:: Beer, N, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Plasma Metabolome Predicts Aortic Stiffness and Future Risk of Coronary Artery Disease and Mortality After 23 Years of Follow‐Up in the General Population
Yazar:: Filip Ottosson, ve diğerleri
Baskı/Yayın Bilgisi: (2024-05-01)

Putative role for the calpain 10 gene in free fatty acid metabolism.
Yazar:: Orho-Melander, M, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

A favorable lifestyle lowers the risk of coronary artery disease consistently across strata of non-modifiable risk factors in a population-based cohort
Yazar:: Kristian Dimovski, ve diğerleri
Baskı/Yayın Bilgisi: (2019-11-01)

Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men
Yazar:: Stanley Teleka, ve diğerleri
Baskı/Yayın Bilgisi: (2022-10-01)

Characterization of the annexin I gene and evaluation of its role in type 2 diabetes.
Yazar:: Lindgren, C, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

A genome-wide search for susceptiblity loci to the metabolic syndrome in the Botnia study
Yazar:: Wieslander, J, ve diğerleri
Baskı/Yayın Bilgisi: (2000)

A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women[S]
Yazar:: Viktor Hamrefors, ve diğerleri
Baskı/Yayın Bilgisi: (2010-03-01)

Genome wide scan and fine-mapping for early onset primary hypertension susceptibility loci in Scandinavian families
Yazar:: Wowern, F, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
Yazar:: Goel, A, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region
Yazar:: Majid Nikpay, ve diğerleri
Baskı/Yayın Bilgisi: (2021-02-01)

Biological, clinical and population relevance of 95 loci for blood lipids.
Yazar:: Teslovich, T, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

The insertion/deletion variation in the α<sub>2B</sub>-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes
Yazar:: Orho-Melander Marju, ve diğerleri
Baskı/Yayın Bilgisi: (2003-11-01)

Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort
Yazar:: Isabel Drake, ve diğerleri
Baskı/Yayın Bilgisi: (2021-03-01)

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
Yazar:: Burtt Nöel P, ve diğerleri
Baskı/Yayın Bilgisi: (2007-09-01)

A healthy dietary metabolic signature is associated with a lower risk for type 2 diabetes and coronary artery disease
Yazar:: Einar Smith, ve diğerleri
Baskı/Yayın Bilgisi: (2022-04-01)

A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8
Yazar:: Isabel Drake, ve diğerleri
Baskı/Yayın Bilgisi: (2017-10-01)

Manhattan++: displaying genome-wide association summary statistics with multiple annotation layers
Yazar:: Grace, C, ve diğerleri
Baskı/Yayın Bilgisi: (2019)

Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease: a cohort study
Yazar:: Thomas Svensson, ve diğerleri
Baskı/Yayın Bilgisi: (2024-04-01)

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
Yazar:: Beer, N, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Circulating protein biomarkers predict incident hypertensive heart failure independently of N‐terminal pro‐B‐type natriuretic peptide levels
Yazar:: Celine Fernandez, ve diğerleri
Baskı/Yayın Bilgisi: (2020-08-01)

Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis.
Yazar:: Stanley Teleka, ve diğerleri
Baskı/Yayın Bilgisi: (2020-01-01)

Growth differentiation factor-15 and incident chronic kidney disease: a population-based cohort study
Yazar:: Xue Bao, ve diğerleri
Baskı/Yayın Bilgisi: (2021-10-01)

Elevated soluble LOX-1 predicts risk of first-time myocardial infarction
Yazar:: Alexandru Schiopu, ve diğerleri
Baskı/Yayın Bilgisi: (2023-12-01)

Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) and Impaired Kidney Function in the Population-based Malmö Diet and Cancer Study
Yazar:: Christina-Alexandra Schulz, ve diğerleri
Baskı/Yayın Bilgisi: (2017-03-01)

Lifestyle and genetic risk of chronic liver disease in metabolically healthy and unhealthy individuals from the general population
Yazar:: Isabel Drake, ve diğerleri
Baskı/Yayın Bilgisi: (2024-08-01)

Dimethylguanidino Valerate: A Lifestyle‐Related Metabolite Associated With Future Coronary Artery Disease and Cardiovascular Mortality
Yazar:: Filip Ottosson, ve diğerleri
Baskı/Yayın Bilgisi: (2019-10-01)

Waist circumference and a body shape index and prostate cancer risk and mortality
Yazar:: Sylvia H. J. Jochems, ve diğerleri
Baskı/Yayın Bilgisi: (2021-04-01)

Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C[S]
Yazar:: S. Hellstrand, ve diğerleri
Baskı/Yayın Bilgisi: (2012-06-01)

Genetic Variants in Lp(a) Lipoprotein and Coronary Disease REPLY
Yazar:: Farrall, M, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Understanding the Function of a Locus Using the Knowledge Available at Single-Nucleotide Polymorphisms
Yazar:: Majid Nikpay, ve diğerleri
Baskı/Yayın Bilgisi: (2021-12-01)

LPA NULL MUTATION GENOTYPING AND QPCR ANALYSIS REFINE KRINGLE ISOFORM ANALYSIS OF LP(A) LEVELS
Yazar:: Kyriakou, T, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

A genome wide scan for early onset primary hypertension in Scandinavians.
Yazar:: von Wowern, F, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis
Yazar:: Eva Bengtsson, ve diğerleri
Baskı/Yayın Bilgisi: (2017-06-01)

Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.
Yazar:: Viktor Hamrefors, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)