Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

<p><strong>BACKGROUND:</strong> Prognostic models to predict the risk of clinical deterioration in acute COVID-19 cases are urgently required to inform clinical management decisions.</p> <p><strong>METHODS:</strong> We developed and validated a multivariabl...

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Main Authors: Gupta, RK, Harrison, EM, Ho, A, Docherty, AB, Knight, SR, van Smeden, M, Abubakar, I, Lipman, M, Quartagno, M, Pius, R, Buchan, I, Carson, G, Drake, TM, Dunning, J, Fairfield, CJ, Gamble, C, Green, CA, Halpin, S, Hardwick, HE, Holden, KA, Horby, PW, Jackson, C, Mclean, KA, Merson, L, Nguyen-Van-Tam, JS, Norman, L, Olliaro, PL, Pritchard, MG, Russell, CD, Scott-Brown, J, Shaw, CA, Sheikh, A, Solomon, T, Sudlow, C, Swann, OV, Turtle, L, Openshaw, PJM, Baillie, JK, Semple, MG, Noursadeghi, M, ISARIC4C Investigators
Format: Journal article
Language:English
Published: Elsevier 2021