Dominant tolerance and linked suppression induced by therapeutic antibodies do not depend on Fas-FasL interactions.
BACKGROUND: Nonlytic anti-CD4 monoclonal antibody therapy can be used to induce transplantation tolerance in rodent models. Such tolerance is often associated with dominant regulation, mediated by CD4+ cells, and characterized by infectious tolerance and linked suppression. Understanding the mechani...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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