Dominant tolerance and linked suppression induced by therapeutic antibodies do not depend on Fas-FasL interactions.

BACKGROUND: Nonlytic anti-CD4 monoclonal antibody therapy can be used to induce transplantation tolerance in rodent models. Such tolerance is often associated with dominant regulation, mediated by CD4+ cells, and characterized by infectious tolerance and linked suppression. Understanding the mechani...

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Bibliografiska uppgifter
Huvudupphovsmän: Honey, K, Cobbold, S, Waldmann, H
Materialtyp: Journal article
Språk:English
Publicerad: 2000