How B cell receptor repertoire sequencing can be enriched with structural antibody data

Next-generation sequencing of immunoglobulin gene repertoires (Ig-seq) allows the investigation of large-scale antibody dynamics at a sequence level. However, structural information, a crucial descriptor of antibody binding capability is not collected in Ig-seq protocols. Developing systematic relat...

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Bibliographic Details
Main Authors: Kovaltsuk, A, Krawczyk, K, Galson, J, Kelly, D, Deane, C, Trück, J
Format: Journal article
Published: Frontiers Media 2017