A needle micro-osmometer for determination of glycosaminoglycan concentration in excised nucleus pulposus tissue

Purpose: Aggrecan is one of the major macromolecular components of the intervertebral disc (IVD) and its loss is an early sign of degeneration. Restoration of aggrecan, and hence of biomechanical properties, is a major objective of biological therapies. At present, assessment of aggrecan concentrati...

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Bibliographic Details
Main Authors: Sivan, S, Merkher, Y, Wachtel, E, Urban, J, Lazary, A, Maroudas, A
Format: Journal article
Language:English
Published: 2013