Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.

Genes and mechanisms involved in common complex diseases, such as the autoimmune disorders that affect approximately 5% of the population, remain obscure. Here we identify polymorphisms of the cytotoxic T lymphocyte antigen 4 gene (CTLA4)--which encodes a vital negative regulatory molecule of the im...

Full description

Bibliographic Details
Main Authors:	Ueda, H, Howson, J, Esposito, L, Heward, J, Snook, H, Chamberlain, G, Rainbow, D, Hunter, K, Smith, A, Di Genova, G, Herr, M, Dahlman, I, Payne, F, Smyth, D, Lowe, C, Twells, R, Howlett, S, Healy, B, Nutland, S, Rance, H, Everett, V, Smink, L, Lam, A, Cordell, H, Walker, N
Format:	Journal article
Language:	English
Published:	2003

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.

Similar Items