MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

CONTEXT: In observational studies, individuals with elevated levels of plasma homocysteine tend to have moderately increased risk of coronary heart disease (CHD). The MTHFR 677C-->T polymorphism is a genetic alteration in an enzyme involved in folate metabolism that causes elevated homocystei...

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Detalles Bibliográficos
Main Authors: Klerk, M, Verhoef, P, Clarke, R, Blom, H, Kok, F, Schouten, E
Formato: Journal article
Idioma:English
Publicado: 2002

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