MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

CONTEXT: In observational studies, individuals with elevated levels of plasma homocysteine tend to have moderately increased risk of coronary heart disease (CHD). The MTHFR 677C-->T polymorphism is a genetic alteration in an enzyme involved in folate metabolism that causes elevated homocystei...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Klerk, M, Verhoef, P, Clarke, R, Blom, H, Kok, F, Schouten, E
Format: Journal article
Sprache:English
Veröffentlicht: 2002