Efficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs

<strong>Background</strong> A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the alignment used, and neglecting the uncertainty in...

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Bibliographic Details
Main Authors: Herman, J, Novák, Á, Lyngsø, R, Szabó, A, Miklós, I, Hein, J
Format: Journal article
Language:English
Published: BioMed Central 2015