The stereocontrolled total synthesis of spirastrellolide A methyl ester. Expedient construction of the key fragments.
Due to a combination of their promising anticancer properties, limited supply from the marine sponge source and their unprecedented molecular architecture, spirastrellolides represent attractive and challenging synthetic targets. A modular strategy for the synthesis of spirastrellolide A methyl este...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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