The stereocontrolled total synthesis of spirastrellolide A methyl ester. Expedient construction of the key fragments.

Due to a combination of their promising anticancer properties, limited supply from the marine sponge source and their unprecedented molecular architecture, spirastrellolides represent attractive and challenging synthetic targets. A modular strategy for the synthesis of spirastrellolide A methyl este...

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Bibliographic Details
Main Authors: Paterson, I, Anderson, E, Dalby, S, Lim, J, Maltas, P, Loiseleur, O, Genovino, J, Moessner, C
Format: Journal article
Language:English
Published: 2012