The stereocontrolled total synthesis of spirastrellolide A methyl ester. Expedient construction of the key fragments.

Due to a combination of their promising anticancer properties, limited supply from the marine sponge source and their unprecedented molecular architecture, spirastrellolides represent attractive and challenging synthetic targets. A modular strategy for the synthesis of spirastrellolide A methyl este...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Paterson, I, Anderson, E, Dalby, S, Lim, J, Maltas, P, Loiseleur, O, Genovino, J, Moessner, C
Format: Journal article
Sprache:English
Veröffentlicht: 2012