Controlling the mobility of oligonucleotides in the nanochannels of mesoporous silica

Oligonucleotides used in gene therapy and silencing are fragile compounds that degrade easily in biological environments. Porous biocompatible carrier particles may provide a useful strategy to deliver these therapeutics to their target sites. Development of appropriate delivery vehicles, however, r...

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Bibliographic Details
Main Authors: Lebold, T, Schlossbauer, A, Schneider, K, Schermelleh, L, Leonhardt, H, Bein, T, Bräuchle, C
Format: Journal article
Language:English
Published: 2012