Controlling the mobility of oligonucleotides in the nanochannels of mesoporous silica
Oligonucleotides used in gene therapy and silencing are fragile compounds that degrade easily in biological environments. Porous biocompatible carrier particles may provide a useful strategy to deliver these therapeutics to their target sites. Development of appropriate delivery vehicles, however, r...
Main Authors: | Lebold, T, Schlossbauer, A, Schneider, K, Schermelleh, L, Leonhardt, H, Bein, T, Bräuchle, C |
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Format: | Journal article |
Language: | English |
Published: |
2012
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