Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: findings from the Pneumonia Etiology Research for Child Health (PERCH) study

Background. Sputum examination can be useful in diagnosing the cause of pneumonia in adults but is less well established in children. We sought to assess the diagnostic utility of polymerase chain reaction (PCR) for detection of respiratory viruses and bacteria in induced sputum (IS) specimens from...

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Main Authors: Thea, DM, Seidenberg, P, Park, DE, Mwananyanda, L, Fu, W, Shi, Q, Baggett, HC, Brooks, WA, Feikin, DR, Howie, SRC, Knoll, MD, Kotloff, KL, Levine, OS, Madhi, SA, O’Brien, KL, Scott, JAG, Antonio, M, Awori, JO, Baillie, VL, DeLuca, AN, Driscoll, AJ, Higdon, MM, Hossain, L, Jahan, Y, Karron, RA, Kazungu, S, Li, M, Moore, DP, Morpeth, SC, Ofordile, O, Prosperi, C, Sangwichian, O, Sawatwong, P, Sylla, M, Tapia, MD, Zeger, SL, Murdoch, DR, Hammitt, LL
Format: Journal article
Published: Oxford University Press 2017