Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: findings from the Pneumonia Etiology Research for Child Health (PERCH) study

Limited utility of polymerase chain reaction in induced sputum specimens for determining the causes of childhood pneumonia in resource-poor settings: findings from the Pneumonia Etiology Research for Child Health (PERCH) study

Background. Sputum examination can be useful in diagnosing the cause of pneumonia in adults but is less well established in children. We sought to assess the diagnostic utility of polymerase chain reaction (PCR) for detection of respiratory viruses and bacteria in induced sputum (IS) specimens from...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Thea, DM, Seidenberg, P, Park, DE, Mwananyanda, L, Fu, W, Shi, Q, Baggett, HC, Brooks, WA, Feikin, DR, Howie, SRC, Knoll, MD, Kotloff, KL, Levine, OS, Madhi, SA, O’Brien, KL, Scott, JAG, Antonio, M, Awori, JO, Baillie, VL, DeLuca, AN, Driscoll, AJ, Higdon, MM, Hossain, L, Jahan, Y, Karron, RA, Kazungu, S, Li, M, Moore, DP, Morpeth, SC, Ofordile, O, Prosperi, C, Sangwichian, O, Sawatwong, P, Sylla, M, Tapia, MD, Zeger, SL, Murdoch, DR, Hammitt, LL
Формат:	Journal article
Хэвлэсэн:	Oxford University Press 2017

Ижил төстэй зүйлс

Should controls with respiratory symptoms be excluded from case-control studies of pneumonia etiology? Reflections from the PERCH study.
-н: Higdon, MM, зэрэг
Хэвлэсэн: (2017)

Introduction to the site-specific etiologic results from the pneumonia etiology research for child health (PERCH) study
-н: Deloria Knoll, M, зэрэг
Хэвлэсэн: (2021)

Introduction to the epidemiologic considerations, analytic methods, and foundational results from the pneumonia etiology research for child health study
-н: O’Brien, KL, зэрэг
Хэвлэсэн: (2017)

The diagnostic utility of induced sputum microscopy and culture in childhood pneumonia
-н: Murdoch, DR, зэрэг
Хэвлэсэн: (2017)

Bayesian estimation of pneumonia etiology: Epidemiologic considerations and applications to the Pneumonia Etiology Research for Child Health study
-н: Knoll, M, зэрэг
Хэвлэсэн: (2017)

Safety of induced sputum collection in children hospitalized with severe or very severe pneumonia
-н: DeLuca, AN, зэрэг
Хэвлэсэн: (2017)

Microscopic analysis and quality assessment of induced sputum from children with pneumonia in the PERCH study
-н: Murdoch, DR, зэрэг
Хэвлэсэн: (2017)

Pertussis-associated pneumonia in infants and children from low- and middle-income countries participating in the PERCH study
-н: Barger-Kamate, B, зэрэг
Хэвлэсэн: (2016)

Addressing the analytic challenges of cross-sectional pediatric pneumonia etiology data
-н: Hammitt, LL, зэрэг
Хэвлэсэн: (2017)

Density of upper respiratory colonization with Streptococcus pneumoniae and Its role in the diagnosis of pneumococcal pneumonia among children aged <5 5 years in the PERCH study
-н: Baggett, HC, зэрэг
Хэвлэсэн: (2017)

The effect of antibiotic exposure and specimen volume on the detection of bacterial pathogens in children with pneumonia
-н: Driscoll, AJ, зэрэг
Хэвлэсэн: (2017)

The enduring challenge of determining pneumonia etiology in children: Considerations for future research priorities
-н: Feikin, DR, зэрэг
Хэвлэсэн: (2017)

Evaluation of pneumococcal load in blood by polymerase chain reaction for the diagnosis of pneumococcal pneumonia in young children in the PERCH Study
-н: Knoll, M, зэрэг
Хэвлэсэн: (2017)

Is higher viral load in the upper respiratory tract associated with severe pneumonia? Findings from the PERCH study
-н: Feikin, DR, зэрэг
Хэвлэсэн: (2017)

Chest radiograph findings in childhood pneumonia cases From the multisite PERCH Study.
-н: Fancourt, N, зэрэг
Хэвлэсэн: (2017)

Colonization density of the upper respiratory tract as a predictor of pneumonia—Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus, and Pneumocystis jirovecii
-н: Park, DE, зэрэг
Хэвлэсэн: (2017)

The etiology of pneumonia in HIV-uninfected children in Kilifi, Kenya: findings from the pneumonia etiology research for child health (PERCH) study
-н: Awori, JO, зэрэг
Хэвлэсэн: (2021)

Detection of pneumococcal DNA in blood by polymerase chain reaction for diagnosing pneumococcal pneumonia in young children From low- and middle-income countries
-н: Morpeth, SC, зэрэг
Хэвлэсэн: (2017)

The etiology of pneumonia from analysis of lung aspirate and pleural fluid samples: Findings from the Pneumonia Etiology Research for Child Health (PERCH) study
-н: Ebruke, BE, зэрэг
Хэвлэсэн: (2020)

Association of C-reactive protein qith bacterial and respiratory syncytial virus–Associated pneumonia among children aged <5 years in the PERCH study
-н: Le, T, зэрэг
Хэвлэсэн: (2017)

Standardization of clinical assessment and sample collection across All PERCH study sites
-н: Crawley, J, зэрэг
Хэвлэсэн: (2017)

Upper respiratory tract co-detection of human endemic coronaviruses and high-density pneumococcus associated with increased severity among HIV-uninfected children under 5 years old in the PERCH study
-н: Park, DE, зэрэг
Хэвлэсэн: (2021)

Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1-59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case-control study
-н: Park, DE, зэрэг
Хэвлэсэн: (2022)

Specimen collection for the diagnosis of pediatric pneumonia.
-н: Hammitt, L, зэрэг
Хэвлэсэн: (2012)

The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology study.
-н: Levine, O, зэрэг
Хэвлэсэн: (2012)

Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management
-н: Katherine E. Gallagher, зэрэг
Хэвлэсэн: (2024-01-01)

Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.
-н: Katherine E Gallagher, зэрэг
Хэвлэсэн: (2024-01-01)

Epidemiology of the Rhinovirus (RV) in African and Southeast Asian Children: A Case-Control Pneumonia Etiology Study
-н: Vicky L. Baillie, зэрэг
Хэвлэсэн: (2021-06-01)

The definition of pneumonia, the assessment of severity, and clinical standardization in the Pneumonia Etiology Research for Child Health study.
-н: Scott, J, зэрэг
Хэвлэсэн: (2012)

A preliminary study of pneumonia etiology among hospitalized children in Kenya.
-н: Hammitt, L, зэрэг
Хэвлэсэн: (2012)

Breathing new life into pneumonia diagnostics.
-н: Murdoch, DR, зэрэг
Хэвлэсэн: (2009)

Standardization of laboratory methods for the PERCH Study.
-н: Driscoll, AJ, зэрэг
Хэвлэсэн: (2017)

Treatment failure among Kenyan children with severe pneumonia--a cohort study.
-н: Webb, C, зэрэг
Хэвлэсэн: (2012)

Evaluation of risk factors for severe pneumonia in children: the Pneumonia Etiology Research for Child Health study.
-н: Wonodi, C, зэрэг
Хэвлэсэн: (2012)

The role of postmortem studies in pneumonia etiology research.
-н: Turner, G, зэрэг
Хэвлэсэн: (2012)

A literature review and survey of childhood pneumonia etiology studies: 2000-2010.
-н: Gilani, Z, зэрэг
Хэвлэсэн: (2012)

Identification and selection of cases and controls in the Pneumonia Etiology Research for Child Health project.
-н: Deloria-Knoll, M, зэрэг
Хэвлэсэн: (2012)

Tracking the Evolution and Antibiotic Resistance Patterns of Streptococcus pneumoniae in Indian Adult Populations through High-Throughput Genome Sequencing
-н: Mr Varun Shamanna, зэрэг
Хэвлэсэн: (2025-03-01)

Clinical spectrum and complications of childhood pneumonia in the era of bacterial conjugate vaccines
-н: S. Madhi
Хэвлэсэн: (2014-04-01)

Digitally recorded and remotely classified lung auscultation compared with conventional stethoscope classifications among children aged 1–59 months enrolled in the Pneumonia Etiology Research for Child Health (PERCH) case–control study
-н: Eric D McCollum, зэрэг
Хэвлэсэн: (2022-02-01)