Endothelial cell metabolism and implications for cancer therapy.
Tumour tissue is characterised by fluctuating oxygen concentrations, decreased nutrient supply, and acidic pH. The primarily glycolytic metabolism of tumour cells contributes to this, with increased glucose consumption and increased lactate secretion. Endothelial cells are particularly challenged wh...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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