PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression

PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression

mRNA modifications play important roles in regulating gene expression. One of the most abundant mRNA modifications is N6,2-O-dimethyladenosine (m6Am). Here, we demonstrate that m6Am is an evolutionarily conserved mRNA modification mediated by the Phosphorylated CTD Interacting Factor 1 (PCIF1), whic...

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מידע ביבליוגרפי
Main Authors: Sendinc, E, Valle-Garcia, D, Dhall, A, Chen, H, Henriques, T, Navarrete-Perea, J, Sheng, W, Gygi, SP, Adelman, K, Shi, Y
פורמט: Journal article
שפה:English
יצא לאור: Elsevier 2019

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