Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

Osteoarthritis is the most common form of arthritis and is a major cause of pain and disability in the elderly. To search for sequence variants that confer risk of osteoarthritis of the hand, we carried out a genome-wide association study (GWAS) in subjects with severe hand osteoarthritis, using var...

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Détails bibliographiques
Auteurs principaux: Styrkarsdottir, U, Thorleifsson, G, Helgadottir, H, Bomer, N, Metrustry, S, Bierma-Zeinstra, S, Strijbosch, A, Evangelou, E, Hart, D, Beekman, M, Jonasdottir, A, Sigurdsson, A, Eiriksson, F, Thorsteinsdottir, M, Frigge, M, Kong, A, Gudjonsson, SA, Magnusson, O, Masson, G, Hofman, A, Arden, N, Ingvarsson, T, Lohmander, S, Kloppenburg, M, Rivadeneira, F
Format: Journal article
Langue:English
Publié: 2014

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