A multi-omics approach to understand mesenchymal stem cell ageing

<p>Mesenchymal stem cell (MSC) ageing is characterised by impaired proliferation and osteoblast differentiation, leading to a reduction in bone mass and bone strength. Recent evidence indicates that transcriptional and epigenetic changes may underlie the impaired MSC functions with age. This t...

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Detalhes bibliográficos
Autor principal: Jiang, C
Outros Autores: Roberts, S
Formato: Tese
Publicado em: 2019