Proteome-wide analysis of disease-associated SNPs that show allele-specific transcription factor binding

A causative role for single nucleotide polymorphisms (SNPs) in many genetic disorders has become evident through numerous genome-wide association studies. However, identification of these common causal variants and the molecular mechanisms underlying these associations remains a major challenge. Dif...

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Bibliographic Details
Main Authors: Butter, F, Davison, L, Viturawong, T, Scheibe, M, Vermeulen, M, Todd, J, Mann, M
Format: Journal article
Language:English
Published: Public Library of Science 2012