Notch receptor-ligand binding and activation: insights from molecular studies.

The Notch receptor is part of a core signalling pathway which is highly conserved in all metazoan species. It is required for various cell fate decisions at multiple stages of development and in the adult organism, with dysregulation of the pathway associated with genetic and acquired diseases inclu...

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Bibliographic Details
Main Authors: Chillakuri, C, Sheppard, D, Lea, S, Handford, P
Format: Journal article
Language:English
Published: 2012