Structural and segregation analysis of the type II collagen gene (COL2A1) in some heritable chondrodysplasias.
Seventy-seven persons with a variety of heritable chondrodysplasias were screened for gross rearrangements of the structural gene encoding the major cartilage collagen, collagen II. None was found. Segregation of the locus (COL2A1) was studied in 19 pedigrees using three restriction site dimorphisms...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1988
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